Pooled data show that no or shorter antibiotic prophylaxis for upper GI bleeding in cirrhosis is very likely noninferior to longer courses for all-cause mortality, challenging long-standing advice.

A shorter course of prophylactic antibiotics, or even no course at all, appeared to be noninferior to longer courses in ...

Targeted vaccines and antiviral prophylaxis are expanding prevention options and redefining ‘safe sex’ for gay, bisexual and ...

Current guidelines for patients with cirrhosis and upper-GI bleeding recommend 5 to 7 days of antibiotic prophylaxis to ...

Prophylactic antibiotic use before tunneled cuffed catheter insertion was not linked to a lower rate of early hemodialysis ...

PJP was associated with high mortality and low prophylaxis rates among immunocompromised patients without HIV infection.

Pemivibart was well tolerated and prophylactic against COVID-19 infection among adult patients with significant immunocompromising conditions.

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There were no available data on other important outcomes. Multicentre, randomised controlled trials comparing antibiotic prophylaxis and placebo or no antibiotic, or one antibiotic and another, for ...

Such experiences indicate that routine antibiotic prophylaxis was ineffective in preventing pulmonary infection in some patients with congestive heart failure.

These data support the thesis that prophylactic antibiotic therapy is of no benefit, and is distinctly hazardous in unconscious patients.