The likes of Brock Purdy, Fred Warner and Christian McCaffrey, among others, did not take part in the preseason opener.

49ers coach Kyle Shanahan told reporters on Monday that star wide receiver Brandon Aiyuk could be back by Week 6. Aiyuk suffered a torn ACL and MCL against the Kansas City Chiefs in a Week 7 game last ...

ARIZONA -- The San Francisco 49ers are not expecting star wide receiver Brandon Aiyuk to be available for their early season battle against the Arizona Cardinals. 49ers coach Kyle Shanahan told ...