Introduction A meta-analysis was performed using individual patient data from the five most recent randomised controlled trials (RCTs) which evaluated corticosteroids in severe alcoholic hepatitis ...
Background High serum levels of interleukin 6 (IL-6) predict poor prognosis in intrahepatic cholangiocarcinoma (iCCA), a malignancy that often develops in a chronically inflamed milieu . Here, tumour ...
Background Colorectal cancer (CRC) exhibits increased levels of arachidonic acid-derived pro-inflammatory derivatives ...
Day case liver biopsies are rarely performed nationally but have been routine practice in selected patients in our hospital since 1989. We have audited our experience of this procedure to compare its ...
We read with great interest the recent study by Lin Huang and colleagues, which demonstrates that glycine supplementation enhances hepatocyte regeneration in chronic hepatitis B (CHB).1 This is a ...
BACKGROUND Butyrate oxidation within the colonocyte is selectively inhibited by hydrogen sulphide, reproducing the metabolic lesion observed in active ulcerative colitis. AIMS To study generation of ...
Background Complications of endoscopic mucosal resection (EMR) of large colorectal polyps remain a concern. Objective We aimed to compare safety and efficacy of cold EMR (without electrocautery) to ...
Correspondence to Professor Michelangelo Foti, Department of Cell Physiology and Metabolism, University of Geneva Faculty of Medicine, Geneve 1206, Switzerland; michelangelo.foti{at}unige.ch Objective ...
Introduction Patients experiencing clinical benefit from vedolizumab in the GEMINI Long term (LTS) (NCT00790933) or VERSIFY (NCT02425111) studies could continue treatment in the vedolizumab extended ...
Introduction Faecal Immunochemical Testing (FIT) is now a core step in the referral and investigation of patients presenting with symptoms of possible colorectal cancer (CRC), as concentrations of Hb ...
Correspondence to Dr Richard C Pollok, Gastroenterology, St George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK; richard.pollok{at}nhs.net Objective Depression is a potential risk ...
Objective: To evaluate the efficacy and safety of long-term budesonide therapy for the maintenance of clinical remission in patients with collagenous colitis. Design: Randomised, placebo-controlled ...
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