Objectives Chorea, characterised by involuntary, irregular movements, is a rare neurological manifestation of antiphospholipid syndrome (APS). The specific clinical features remain unclear. This study ...

Background SLE is an independent risk factor for cardiovascular disease (CVD). This study aimed to determine which among QRISK2, QRISK3, Framingham Risk Score (FRS), modified Framingham Risk Score ...

Objective To investigate the role of curcumin in the treatment of lupus nephritis (LN) by inhibiting the migration of neutrophils and the underlying mechanism involved. Methods Two lupus mouse models, ...

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Objectives The lupus low disease activity state (LLDAS) allows for certain clinical and/or serological activity of SLE, ...

Malignancy risk in systemic lupus erythematosus (SLE) is about 15% higher than the general age-and-sex-matched population. Hematologic cancers, especially B-cell lymphomas, are about three-fold ...

Hemophagocytic lymphohistiocytosis (HLH) is a well-recognised complication of systemic lupus erythematosus (SLE). In one small case series, HLH was noted in approximately 5% of patients with lupus. 1 ...

In the past decade, the world of publishing has undergone rapid changes with the proliferation of online journals and the advances of the open access movement. Consequently, the roles of authors and ...

Case 2: A 28-year-old female with relapsing lupus nephritis A young female, 28 years, received a diagnosis of systemic lupus erythematosus at the age of 11 years (in London, UK), it was characterized ...

Systemic lupus erythematosus (SLE) is a heterogeneous disease characterised by abnormalities in cellular and humoral immunity. The clinical complexity of SLE patients also comprise dysregulation of ...

Systemic lupus erythematosus (SLE) is associated with increased expression of genes regulated by Type I interferon (IFN) in 50–70% of patients. 1 Previous studies, including our own, have demonstrated ...