Top wide receiver Brandon Aiyuk is expected to remain sidelined through at least Week 6 as he is still recovering from a torn ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

The 49ers likely have no intention of playing starter Christian McCaffrey in the preseason, backup Isaac Guerendo is out for ...

The 49ers are limiting Christian McCaffrey's training camp reps to keep the running back healthy for the season opener and ...

When the 49ers offense is healthy, it's one of the best in the NFL. Unfortunately, their offense wasn't healthy last year, and it isn't healthy now.

Christian McCaffrey, Kyren Williams, & Najee Harris have carried heavy workloads in their NFL careers. Injury concerns will raise caution in fantasy football.

A high ankle sprain could keep Jordan Watkins from covering for Brandon Aiyuk, Demarcus Robinson when season starts.

Christian McCaffrey credited his wife, Olivia Culpo, for taking care of their newborn daughter while he's at San Francisco ...

Evaluating the risk-factors of Christian McCaffrey and his ability to be drafted in the first round of your fantasy football ...

Two top contenders this year face off in the preseason opener, with the San Francisco 49ers hosting the Denver Broncos. However, many fans are wondering whether stars Christian McCaffrey and Bo Nix ...

Christian McCaffrey was the number one draft pick in fantasy football leagues in 2024, but he missed nearly the entire season.