Animal models from the Jackson Laboratory are available that reflect the genetic diversity of human populations. Taking genetic diversity into account is particularly important in basic research or ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Animal models continue to be a mainstay of basic research and preclinical studies. But since animals such as mice only approximate humans, they may generate findings of limited clinical relevance.

New computer models predict the risk of side effects from heart drugs more accurately than animal models. Researchers from the University of Oxford (UK) have developed computer simulations that are ...

Preclinical testing is vital for assessing the safety profiles and potential efficacy of new therapeutics in development. Animal testing is one of two routes usually selected for the preclinical stage ...

Tendinopathy is a common and significant clinical problem characterised by activity-related pain, focal tendon tenderness and intratendinous imaging changes. Recent histopathological studies have ...

Animal testing remains to be a vital part of modern preclinical testing. While the ethics of the use of animals in medical testing remains keenly debated, it is still generally accepted worldwide and ...

Torie Bosch is the First Opinion editor at STAT. First Opinion is STAT’s platform for interesting, illuminating, and provocative articles about the life sciences writ large, written by biotech ...

I recently read a highly-detailed, comprehensive, science-based report called The Research Modernization Deal 2021. It unambiguously shows that numerous experiments on nonhuman animals (animals) fail ...