Background Pancreatic ductal adenocarcinoma (PDAC) is largely refractory to immune checkpoint blockade, owing to its ...

Researchers at the University of Liverpool have discovered that SYCP1, a protein previously thought to function only during ...

Researchers at the University of Liverpool have discovered that SYCP1, a protein previously thought to function only during ...

We read with great interest the recent study by Lau et al , who reported distinct intrahepatic hepatitis B virus (HBV) ...

The epigenetic modifier MLL4 has an unassuming name—the 4, for instance, indicates it's just one in a family of such ...

A study has shown that aging disrupts gene transcription and RNA processing, reducing the expression of long neuronal genes ...

Prime Medicine, Inc. wins arbitration vs. Beam Therapeutics Inc., advancing PM647 for AATD. Read more on PRME and BEAM stocks ...

A lot of things need to go right on a molecular level for immune cells to launch an adaptive response to an infection. B cells can produce different classes of antibodies tailored for specific ...

Much of the genome is made up of repetitive DNA sequences that trace back to ancient mobile elements, many of which have lost ...

Mitochondria lack nucleotide excision repair; however, mitochondrial DNA (mtDNA) is resistant to mutation accumulation following DNA damage. These observations suggest additional damage sensing or ...

This study presents DeepTX, a valuable methodological tool that integrates mechanistic stochastic models with single-cell RNA sequencing data to infer transcriptional burst kinetics at genome scale.