The full Senate voted 51-49 on Thursday to advance Hegseth's nomination, paving the way for a final confirmation vote Friday.
Republicans say they are confident that Hegseth, who has been accused of alcohol and domestic abuse, will ultimately be confirmed to lead the Pentagon.
The vote broke the Senate filibuster and sets up a final confirmation vote, which will likely take place Friday. Democrat John Fetterman voted against advancing Hegseth for secretary of defense.