Aims ‘Diagnostic odyssey’ encompasses time from initial disease recognition or symptom onset to final diagnosis as experienced by patients with rare genetic diseases and their families. General ...

Background and objective Cardiorespiratory polygraphy (CRP) is the predominant technology used to diagnose obstructive sleep apnoea (OSA) in tertiary centres in the UK. Nocturnal pulse oximetry (NPO) ...

In this review, we provide a state of the art of liver transplantation in children, as the procedure is now carried out for more than 30 years and most of our paediatric colleagues are managing these ...

The heart and lungs work closely to meet the tissues’ oxygen demands. If the balance between oxygen demand and supply becomes disturbed in critical illness, tissue hypoxia and cell death can rapidly ...

Aims: To investigate whether weight category (underweight, average weight, overweight, and obese) at age 7.5 predicts bullying involvement at 8.5 years. Models were tested separately for boys and ...

Aim This literature review seeks to establish whether sufficient evidence showing an additional benefit of continuous glucose monitoring (CGM) on diabetes outcomes compared to intermittent self ...

Our aim was to develop guidance for general paediatricians and primary care physicians in diagnosing and managing cow’s milk protein allergy in infants. The guidelines were developed by discussion ...

Objectives Babies born to mothers living in more deprived areas are at a higher risk of dying during the neonatal period.1 Pre-term and unwell term babies are cared for in neonatal intensive units ...

Aims Up to 2% of all pregnancies are conceived by in vitro fertilisation (IVF) in the UK. IVF methodologies include fresh and frozen-thawed embryo transfer. Neonates conceived by frozen-thawed IVF are ...

Objective Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is an inherited adrenal steroid synthesis ...

AIM To determine the incidence of hypocalcaemia in critically ill children with meningococcal disease. METHODS In a prospective cohort study, 70 of 80 patients admitted consecutively with a clinical ...

Introduction Deliberate self harm (DSH) is a major public health issue affecting 1 in 15 young people in the UK. Madge et al (2008) reported that over 70% of 15–16 year-olds admitted to self-harming ...