rmdopen.bmj6d
Targeting the IL-17A pathway for therapy in early-stage tendinopathy
Objectives Tendinopathy is a frequent clinical problem and represents an extraordinary health economic and socioeconomic ...
rmdopen.bmj3d
Lung ultrasound outperforms symptom-based screening to detect interstitial lung disease associated with rheumatoid arthritis
Objectives Interstitial lung disease associated with rheumatoid arthritis (RA-ILD) is linked to high mortality. Currently, ...
rmdopen.bmj3d
Efficacy and safety of rituximab in the treatment of eosinophilic granulomatosis with polyangiitis
Introduction Eosinophilic granulomatosis with polyangiitis (EGPA) is a subset of antineutrophil cytoplasmic antibodies (ANCA) associated vasculitis with distinct pathophysiological mechanisms, ...
rmdopen.bmj2d
Cancer immunotherapy-induced rheumatic diseases emerge as new clinical entities
Immune checkpoint inhibitors (ICIs) are newly approved treatments for advanced malignancies that are increasing survival. The mechanism of these drugs, non-specifically activating T cells, also leads ...
rmdopen.bmj10d
From patients with arthralgia, pre-RA and recently diagnosed RA: what is the current status of understanding RA pathogenesis?
It is believed that therapy for rheumatoid arthritis (RA) is the most effective and beneficial within a short time frame around RA diagnosis. This insight has caused a shift from research in patients ...
rmdopen.bmj2d
Getting prepared for the silver wave: challenges in conducting rheumatic and musculoskeletal disease research in older adults
Research in older adults diagnosed with rheumatic and musculoskeletal diseases (RMDs) comes with unique challenges, as these patients often face consequences of ageing, such as multimorbidity, ...
rmdopen.bmj12d
Subchondral bone attenuation coefficient utility of the sacroiliac margins to differentiate spondyloarthritis and osteitis condensans ilii
Introduction Differentiating ankylosing spondylitis (AS) from osteitis condensans ilii (OCI) remains challenging for clinicians. The aim of this study was to determine whether Subchondral Bone ...
rmdopen.bmj6d
Patients with ankylosing spondylitis present a distinct CD8 T cell subset with osteogenic and cytotoxic potential
Correspondence to Dr Mariagrazia Uguccioni; mariagrazia.uguccioni{at}irb.usi.ch; Dr Valentina Cecchinato; valentina.cecchinato{at}irb.usi.ch Conclusions Our results shed light on a new molecular ...
rmdopen.bmj8d
SIGLEC1 is a biomarker of disease activity and indicates extraglandular manifestation in primary Sjögren's syndrome
Objectives To evaluate the interferon (IFN) biomarkers sialic acid binding Ig like lectin 1 (SIGLEC1, CD169) and IFN-γ-inducible protein-10 (IP-10) in patients with primary Sjögren's syndrome (pSS).