The discovery could lead to a new treatment for millions of people with obesity and type 2 diabetes who do not respond well to current treatments.

The UK and Romania have signed a defence treaty as the two nations continue their efforts to support war-torn Ukraine. Defence Secretary John Healey and his counterpart, Angel Tilvar, signed the ...

Shadow equalities minister Claire Coutinho has pressed the Government to clarify the definition of sex. Equalities minister Bridget Phillipson said it was “important that providers have clarity in ...

An 18-year-old man accused of killing three young girls in a knife attack at a dance class in Southport and producing the deadly toxin ricin will go on trial next year. Axel Rudakubana covered his ...

Nigel Farage has claimed there is “outright hostility” in the US to the UK’s deal with Mauritius to relinquish sovereignty over the Chagos Islands. The Reform UK leader, who has been a long-time ...

Sixteen people suffered minor injuries after a lorry and bus carrying schoolchildren collided in Leicestershire. The bus and the HGV crashed on the A46 northbound near to Syston at around 9.30am on ...

A “fairytale” picnic cottage enjoyed by Queen Victoria on her visits to Balmoral has been saved from ruin by a conservation charity.

Spy-accused former soldier Daniel Khalife had a 30-minute phone conversation with an Iranian agent while posted at a US army base, a court has heard. The three calls “rekindled” Iran’s interest in ...

Marcus Osborne fatally attacked his former partner, Katie Higton, and her new boyfriend Steven Harnett in Huddersfield, West Yorkshire, in May 2023.

Prime Minister Sir Keir Starmer has said he will ensure meetings take place with ministers to help return a Northern Irish toddler to his mother, after his father in Lebanon ignored a court order to ...

Cornwall Council’s Conservative Cabinet has thrown out a proposition to charge Newquay airport passengers an extra £10 fee, suggesting that if it was introduced it would lead to Ryanair immediately ...

Italian President Sergio Mattarella has sharply rebuked Elon Musk for weighing in on Italian court rulings that have set back ...