The "Dirty Neck" Sign is More Than Skin Deep! When a patient walks in with hyperpigmented, velvety plaques on the neck (Acanthosis Nigricans) often accompanied by Skin Tags (Acrochordons), your diagnosis shouldn't stop at the skin. This is the hallmark cutaneous sign of Insulin Resistance. 🚨 The Clinical Approach: Screen for Metabolic Syndrome: Even if fasting glucose is normal, check for HOMA-IR or post-prandial spikes. The patient is likely pre-diabetic or at high risk for Type 2 Diabetes. Ma
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