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YouTubeBBC World Service
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Metformin doesn’t work by forcing your pancreas to make more insulin like many people think. Its main job is actually in the liver—helping reduce excess glucose production, improving insulin sensitivity, and helping your body use sugar more efficiently. That’s why it remains one of the first-line treatments for type 2 diabetes. #Metformin #Diabetes #Type2Diabetes #Pharmacology #HealthcareEducation
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TikTokexplainique
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For over 60 years, we thought metformin worked mainly through the liver and gut. But new research suggests the brain may play a major role too. This study identified a specific brain pathway (Rap1 in the hypothalamus) that appears critical to metformin’s glucose-lowering effects, potentially reshaping how we understand one of the world’s most prescribed diabetes medications. Source: Sci. Adv. 2025;11:eadu3700
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